
For patients with hormone receptor positive breast cancer
There are three different receptors that are commonly found in breast cancer cells: the estrogen receptor (ER), the progesterone receptor (PR), and the human epidermal growth factor receptor 2 (HER-2). When the hormones estrogen and progesterone attach to their receptors, they are activated and fuel cancer growth. Active HER-2 also fuels cancer growth.
For patients with triple negative breast cancer (TNBC)
Triple negative breast cancer represents 10% to 15% of all breast cancers. A TNBC diagnosis means that the cancer cells have tested negative for the 3 different receptors that are commonly found on breast cancer cells: the estrogen receptor (ER), the progesterone receptor (PR), and the human epidermal growth factor receptor 2 (HER-2).