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Condition: Relapsed Or Refractory Chronic Myelomonocytic Leukemia

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and recommended Phase 2 dose (RP2D) of MK-0482. There are 2 parts of this study. Part 1 is a dose escalation which will follow an accelerated titration design (ATD) for participants with relapsed/refractory (R/R) AML or CMML. Part 2 is a dose expansion for participants with R/R AML.

A Study to Evaluate MK-0482 for Relapsed/Refractory Acute Myeloid Leukemia or Chronic Myelomonocytic Leukemia

October 9, 2022

By clique_admin

The purpose of this study is to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and recommended Phase 2 dose (RP2D) of MK-0482. There are 2 parts of this study. Part 1 is

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